
Quick Links
- Chemistry Basics
- All Chemistry Recipes
Just as you can craft your own equipment and cook your own meals, you can also mix up your own medicine in Rune Factory 4. In fact, with the Chemistry Set you can be so self-reliant that you even make up special fertilizers for all of your farming needs.
RELATED: Rune Factory 4 Special: Complete Guide To Cooking
It won't be far into the game that you start making your own supplies and improving your chemistry skill. Not only will this help you survive on your perilous journeys outside Selphia, but it can even be quite the handy money-making strategy!
Updated on June 14, 2023: We've updated this guide covering chemistry basics and all the chemistry recipes so you can be a medicine master in Rune Factory 4!
Chemistry Basics
Once you have acquired the appropriate license via an order, you can purchase Chemistry Labs from either Jones or Nancy when they are working at the clinic. This will cost you some gold, some lumber, and some material stone.
Once you have the Chemistry Set installed, you can start making restorative items, farming items, cooking ingredients, and eventually even stat boosters.
When using the Chemistry Set, you will use Rune Points (RP) whenever you attempt a recipe.
If the item's level is higher than your chemistry level, it will cost more RP to attempt to make it and there is a chance the attempt could outright fail — this will leave you with an Object X, a mysterious item that can be surprisingly useful.
You can learn recipes in-game by consuming Medicine Bread bought from Porcoline or acquired from festivals.
Alternatively, you could follow the recipes listed in this guide by selecting the "Do not use recipe" option, though it costs considerably more RP the first time you make something this way.
All Chemistry Recipes
When an ingredient is listed in italics, that means you can use any item of that ingredient's category.
Restorative Items
Item
Level
Recipe
Recovery Potion
3
Medicinal Herb, Green Grass
Roundoff
13
Black Grass, Black Grass
Recovery Potion
15
Blue Grass
Para-Gone
18
Indigo Grass, Indigo Grass
Healing Potion
20
Medicinal Herb, Red Grass
Cold Medicine
22
Orange Grass, Toyherb
Antidote Potion
25
Antidote Grass, Toyherb
Roundoff
28
Moondrop
Para-Gone
31
Pink Cat
Cold Medicine
32
Charm Blue
Mystery Potion
33
Medicinal Herb, White Grass
Antidote Potion
38
Cherry Grass
Healing Potion
40
Pom-Pom Grass
Magical Potion
45
Medicinal Herb, Elli Leaves
Formuade
46
Heavy Spice, Lamp Grass, Ironleaf, Powders and Spores, Liquids
Mystery Potion
60
Autumn Grass
Formuade
65
Hot-Hot Fruit
Magical Potion
70
Fireflower
Invinciroid
76
Noel Grass, Emery Flower, Autumn Grass, Hot-Hot Fruit, Formuade
Invinciroid
86
Giant Hot-Hot Fruit, Formuade
Love Potion
87
Emery Flower, Pink Melon, Strawberry, Honey, Hot-Hot Fruit, Grape Liqueur
Love Potion
97
Great Emery Flower
Cooking Items
Item
Level
Ingredients
Sweet Powder
5
Apple
Sour Drop
7
Orange
Mixed Herbs
8
Green Grass, Toyherb
Heavy Spice
10
Purple Grass
Farming Items
Item
Level
Recipe
No Rot α
26
Withered Grass, Toyherb
Formula A
29
Withered Grass, Blue Grass, Black Grass
Wettable Powder
30
Charm Blue, Cherry Grass
Greenifier
34
Withered Grass, Indigo Grass, Moondrop Flower
Formula B
41
Yellow Grass, Pink Cat, 4-Leaf Clover
No Rot ß
50
Withered Grass, Red Grass, 4-Leaf Clover
Minimizer
53
Ironleaf
Giantizer
57
Lamp Grass
Greenifier+
64
Withered Grass, Orange Grass, Corn
Formula C
72
White Grass, Fireflower, Corn
Stat Boosters
Item
Level
Recipe
The Protein
80
Red Crystal, Red Crystal, Spinach, Powders and Spores, Liquids
Intelligencer
82
White Crystal, White Crystal, Eggplant, Powders and Spores, Liquids
Vital Gummi
83
Blue Crystal, Blue Crystal, Bok Choy, Powders and Spores, Liquids
Heart Drink
85
Green Crystal, Green Crystal, Ironleaf, Powders and Spores, Liquids
The Protein
90
Big Red Crystal
Intelligencer
92
Big White Crystal
Vital Gummi
93
Big Blue Crystal
Heart Drink
95
Big Green Crystal
Leveliser
96
Emery Flower, 4-Leaf Clover, Noel Grass, Autumn Grass, Fireflower, Hot-Hot Fruit
Leveliser
99
Great Emery Flower, Great 4-Leaf Clover
NEXT: Rune Factory 4 Special: Complete Romance Guide