Diablo 4 Vessel of Hatred: Complete Guide to All Runewords and Their Effects

Overview
- Activation of Invocation Runes is reliant on the offerings generated by Ritual Runes — achieving a balance is key for maximum effectiveness.
- The synergy between Ritual and Invocation Runes allows players to create unique Runewords in Diablo 4, each with distinct effects.
- The recently launched Vessel of Hatred expansion introduced additional Runewords and revised existing ones, significantly influencing the Season 7 meta.
The launch of Diablo 4‘s first expansion, Vessel of Hatred, alongside the Hatred Rising Season 6 content, has brought a plethora of new gameplay mechanics. Among the noteworthy features, which also include Mercenaries, the Dark Citadel raid, and the Spiritborn class, is the reintroduction of the Runes and Runewords system. Players can create Runewords by combining a Ritual Rune with an Invocation Rune within a two-socket piece of equipment.
The outcome of this combination—its trigger and effect—hinges on the specific Ritual and Invocation Runes employed. It’s crucial to monitor the quantity of Offerings each Rune generates and requires, as this directly impacts the consistency with which players can activate Runeword effects in Diablo 4. A Ritual Rune that produces only 5 Offerings will struggle to empower an Invocation Rune that necessitates 1000 Offerings.
Updated January 23, 2025, by Abigail Angell: The inception of the Season of Witchcraft has introduced three fresh Runewords to Diablo 4: Nagu, Igni, and Chac. This season also features adjustments to 15 existing Runewords from the Vessel of Hatred expansion. These balancing efforts, anticipated following the introduction of such a crucial mechanic, are set to significantly alter the gameplay meta in Season 7.
Comprehensive List of Ritual Runes in Diablo 4
Detailed Insight into D4 Ritual Runes: Triggers and Offerings
Within Diablo 4, all Ritual Runes act as Trigger runes. Marked by a burning yellow engraving and oriented upward in your inventory, these Runes are designed to be inserted into the Top slot of a two-socketed item.
When executing the prescribed action associated with each Ritual Rune, players will generate a specified amount of Offerings, which will enhance the effect of the corresponding Invocation Rune. By successfully fulfilling the Offerings requirement for an Invocation Rune through repeated action, players can activate its effects.
Rune Name Trigger Action Offerings Generated Rarity Body Lucky Hit: Boosted up to a 100% chance against Injured enemies 10x Offerings Legendary Bac Travel 5 meters 50x Offerings Legendary Cem Cast Evade 75x Offerings Magic Cir Use the same non-Channeled skill three times consecutively 50x Offerings Magic Sound Become Injured while Crowd Controlled 1000x Offerings Rare Fire Store offering every 0.3 seconds; cast a non-Basic Skill to gain stored offerings (up to 500 Offerings) 25x Offerings Legendary Who Lose 1% of your Max Life 2x Offerings Rare Lith Stand still for 0.3 seconds 25x Offerings Legendary Money Cast two Mobility or Macabre Skills 100x Offerings Magic Like Keep at least one active summon for 5 seconds, gaining Offerings for each up to 6 100x Offerings Legendary Neo Deal damage after not taking any within 2 seconds 200x Offerings Rare Night Inflict a Crowd Control effect that is not Slow or Chill 10x Offerings Rare Little Consume 5% of your max Primary Resource 5x Offerings Rare To that Cast a non-Channeled Core Skill 25x Offerings Legendary Ur Your Minion or Companion kills an enemy or falls in battle 10x Offerings Magic Score Evoke a Skill from another class 150x Offerings Legendary Okay Consume a Healing potion 200x Offerings Magic Yul Cast a Skill with a cooldown 50x Offerings Legendary I will Use an Ultimate Skill 150x Offerings Magic Comprehensive List of Invocation Runes in Diablo 4
Detailed Insight into D4 Invocation Runes: Effects and Offerings
All Invocation Runes serve as Effect or Ability runes in Diablo 4. Characterized by a purple engraving and oriented downward in your inventory, these Runes are designed to occupy the Bottom slot of a two-socketed item.
Once the required Offering threshold for an Invocation Rune has been met through accumulated Offerings from your Ritual Rune, the corresponding Effect or Ability defined on the Invocation Rune will become active. Players can exceed the Offering requirements, resulting in a beneficial Overflow Effect that enhances the Rune’s impact.
Most Invocation Runes have a cooldown period—typically one second. However, some may require two to six seconds to recharge, particularly those that grant skills from other classes. It’s essential to monitor the purple buff on your UI to keep track of the Offerings needed for the effect to activate.
Rune Name Rune Effect Overflow Effect Offerings Required Rarity Ceh Summons a Spirit Wolf to attack enemies for 8 seconds Summons multiple wolves 100x Offerings Magic Sure Calls Druid Lightning Bolts to strike a nearby foe Generates additional Lightning Bolts 20x Offerings Rare Eom Reduces active cooldowns by 0.25 seconds Further cooldown reductions 100x Offerings Legendary Even Gains 2.5% Crit Chance for 5 seconds, maxing at 25% Stackable Crit Chance 25x Offerings Magic Yes Replaces your next Evade with the Sorcerer’s Teleport, dealing damage and granting Unstoppable Stores excess Offerings 250x Offerings Legendary Get Evoke the Spiritborn’s Vortex to damage and pull enemies Increases Vortex size 500x Offerings Rare Lac Evoke the Barbarian’s Challenging Shout to reduce damage dealt Enhances Duration 800x Offerings Rare Lum Restores 1 of your Primary Resources Increases Resource Restoration 5x Offerings Magic Of Leaves the Necromancer’s Desecrated Ground for 3 seconds, damaging enemies within Increases Duration 100x Offerings Magic Courage Gains a Shadow from the Rogue’s Dark Shroud, reducing damage taken per Shadow Stacks multiple Shadows 150x Offerings Rare Down Evoke the Rogue’s Countering Concealment, granting Dodge Chance, Movement Speed, Unstoppable, and Stealth Increases Duration 700x Offerings Rare Ohm Evoke the Barbarian’s Enhanced War Cry, increasing Movement Speed and Damage output Augments Duration 500x Offerings Legendary This Evoke the Druid’s Dancing Bolts, which automatically target enemies Increases Bolts spawned 25x Offerings Magic Gakh Your next non-Basic Skill cast uses all Primary Resources, dealing up to a 100% damage increase Increases Damage 400x Offerings Rare Via Restores an Evade charge and provides a 10% movement speed boost for 5 seconds, stacking up to 50% Enhances Duration 400x Offerings Magic What Evoke the Druid’s Earthen Bulwark to gain a protective Barrier Increases Duration 800x Offerings Rare Of Evoke the Spiritborn’s Pestilent Swarm to damage enemies Increases Swarm count 30x Offerings Magic Answer Evoke the Necromancer’s Abhorrent Iron Maiden, countering enemies and healing you upon their death Damage increases by 1% per Offering used 100x Offerings Magic Tec Evoke the Barbarian’s Earthquake, dealing area damage to enemies Increases Effect radius 50x Offerings Magic Thul Evoke the Sorcerer’s Mystical Frost Nova, inflicting Freeze and Vulnerability on enemies Expands Area of Effect 400x Offerings Rare Ton Evoke the Sorcerer’s Meteorites, damaging enemies in their immediate vicinity Increases number of Meteorites spawned 20x Offerings Magic Again Evoke the Rogue’s Stun Grenades, stunning and damaging enemies Increases number of Grenades spawned 25x Offerings Magic Tzic Evoke the Spiritborn’s Concussive Stomp, dealing damage and knocking down enemies Damage increases by 1% per Offering used 200x Offerings Rare Vex Gain +1 to all Skills for 7 seconds Increased Skill Ranks (up to 3) 150x Offerings Legendary What Evoke the Necromancer’s Horrid Decrepify, slowing and reducing enemy damage, allowing Executions Enhances Duration 100x Offerings Rare Solution Gains 20% Max Life for 6 seconds Increases Maximum Life 300x Offerings Rare Khan Your next Skill cast guarantees an Overpower and Critical Hit Additional 1% damage per 10x Offerings 700x Offerings Legendary Yom Evoke the Druid’s Petrify, stunning enemies and enhancing Critical Hit Damage against them Increases Stun Duration 500x Offerings Legendary Zec Reduces your active Ultimate Cooldown by 1 second Cooldown reduction 100x Offerings RareSource & Images
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