All the Anime Crossover Defense artifacts are based on items and accessories from a range of series! You’ve got the Hollow Mask, the Hogyoku, the Uta Uta, and so much more.

Head to the official Anime Crossover Defense page to learn more. To learn about another useful feature in the game, read our Anime Crossover Defense Traits guide!

Anime Crossover Defense Artifacts

Artifacts are equippable items that provide a unit with new skills and buffs!

Eternal Eye

Based on the Mangekyou Sharingan from Naruto.

  • Genjutsu
    • Unlocks at rank 5
    • Order the enemy to walk in the wrong direction
  • Black Flames
    • Inflicts the enemy with black flames

Black Notebook

Based on the Death Note book from Deathnote.

  • Fate Written
    • Depending on the HP of an enemy, you have a chance to execute them immediately

Philosopher’s Stone

You can probably guess, but this artifact is based on the same stone from Fullmetal Alchemist.

  • Equivalent Exchange
    • When the equipped unit defeats an enemy, its overall DMG gets a buff

Key of Kings

Based on the Bab-ilu from Fate.

  • King’s Vault
    • Placement cost is decreased
  • King’s Treasure
    • Unlocks at rank 5
    • The cost to upgrade the unit is decreased

Vampire Mask

  • Vampire Lord
    • Summons a zombie to help in battle
  • Hemorrhage
    • Unlocks at rank 5
    • Inflicts the enemy with a damage over time debuff called Bleed
      • This debuff can stack!

Hollow Mask

Based on the Vizard Mask of Ichigo from Bleach.

  • Hollow Mask
    • Overall DMG gets a boost for a period of time

Dragon Radar

Based on the Dragon Ball Radar from Dragon Ball.

  • Dragon Sphere Search
    • Obtain a Dragon Sphere after the 2nd wave of a battle
    • Find all 7 Dragon Spheres to make a wish

Hat of the CEO

Based on Speedwagon’s hat from Jojo’s Bizarre Adventure.

  • Opportunist
    • The amount of money you earn is increased

Divine Eye

Based on the Rinnegan from Naruto.

  • Superior Dojutsu
    • Defends against stun attacks
    • All stats increase slightly
  • Elemental Mastery
    • Unlocks at rank 5
    • Increases the power of the unit by a huge amount

Cursed Finger

Based on Sukuna’s Cursed Fingers from Jujutsu Kaisen.

  • Everlasting Curse
    • Damage over time attacks last longer
  • King of Curses
    • Damage over time deals more DMG

Nimbus

Based on the Flying Nimbus from Dragon Ball.

  • Cloud Transportation
    • The placement cost for the unit is decreased but its max placement count is lowered

Strand of a Hero’s Hair

Inspired by the blonde hair of All Might from My Hero Academia.

  • One For All!
    • Knock back enemies with an attack

Hogyoku

Based on the Hogyoku from Bleach.

  • Metamorphosis
    • The unit’s DMG gets a boost after a few waves
  • Desire Materialization
    • Unlocks at rank 5
    • The unit’s DMG is increased
    • The cost to upgrade is decreased

Uta Uta

Based on the Uta Uta no Mi from One Piece.

  • Joyous Song
    • Increases the power of the unit

Adele Wilson

Editor

    With experience working for GameRant and in SEO copywriting, Adele loves to combine her adoration for gaming with her writing craft. She'll talk your ear off about anything fantasy, and if she's not typing away at her desk, she's probably playing an RPG somewhere, watching anime, or reading a book.