AMD Radeon Setup: Best Settings for Peak Performance (Windows Settings Guide)

Optimizing your AMD graphics card ensures you achieve the best gaming experience. Whether it’s your first setup or you want improved performance, this guide covers every important adjustment without leaving anything out.
Initial Windows and Driver Setup
Start by searching for Settings on your PC. Under the Gaming section, turn off the Game Bar to eliminate unnecessary overlays. Then, activate optimizations for windowed games to reduce input latency.
Under Advanced Graphics Settings, ensure you select your dedicated AMD Radeon graphics card rather than integrated graphics. Also, manually add your frequently used GPU applications for prioritized performance.
Next, download the latest AMD drivers by visiting the AMD Drivers and Support page. You can either allow auto-detection or manually pick your series like Radeon RX 6000. Once installed, access AMD Software: Adrenalin Edition, and ensure your drivers are up to date. If updates are needed, install them immediately.
Fine-Tuning Your AMD Settings for Gaming
Inside the Gaming section of AMD Software, under Graphics, choose Custom. Set your GPU as the primary card. Then enable Radeon Anti-Lag, while disabling Radeon Boost, Chill, Frame Sharpening, and Enhanced Sync for the best input performance.
If available, leave Fluid Motion Frames 2.1 disabled outside of games to avoid added latency. For Anti-Aliasing, use application settings, and for Anisotropic Filtering, choose based on your GPU strength — 2x for weaker cards, 8x or 16x for stronger GPUs. Set Texture Filtering Quality to Performance, disable Surface Format Optimization, and keep Tessellation Mode on AMD Optimized.
In Display Settings, adjust Color Depth to 10 BPC if supported, disable display color enhancements, and set Custom Color with a Saturation level of 140 for richer visuals. Disable HDCP Support under Overrides.
In Performance > Tuning, enable AMD Smart Access Memory if available. You may need to activate Resizable BAR in your BIOS.
Under System Settings, disable Issue Detection to save background resources.
Additional Boosting With Network and Optimization Tools
Fix packet loss and ping issues using NoPing software. After downloading it, select your game and choose the nearest server. Optimize settings like disabling Chrome Telemetry, Edge Telemetry, Dynamic Ticks, and more to reduce input latency and boost FPS.
Create a System Restore Point labeled “Radeon” to back up your new settings safely before applying deeper optimizations.
Use the AMD Radeon Optimization Pack that includes:
Latency Tweaks: Disabling memory compression and unnecessary timers.
RAM Optimizations: Registry files based on your RAM size.
GPU Prioritizations: Ensuring AMD GPUs work at full efficiency.
Windows DVR Tweaks: Enhancing system power performance.
Temporary File Cleaning: Deleting unused temp files safely.
After completing these tweaks, go back to your AMD Software, reset your Shader Cache, and restart your PC to fully apply the performance improvements.
Final Steps for Peak AMD Settings Performance
Once your PC restarts, you’ll notice significant FPS boosts, lower input lag, and overall smoother gameplay. These AMD settings not only enhance your visuals but also guarantee a more competitive edge across titles like Fortnite, Valorant, and many more.
By consistently maintaining driver updates, clearing shader cache, and minimizing background services, your system will stay optimized for any gaming challenge ahead.