Scientist Supreme

Villain| Global| Tech| Support| A.I.M| Orchis A mad scientist who converts negative effects to positive effects while healing her allies.

Character Abilities

Serum Pistol

– 1 +

Field Trials

– 1 +

Retro Vaccination

– 1 +

Mad Science

– 1 +

Passive – Mad Science, on spawn, Marvel Strike Force Scientist Supreme gains 50% Speed Bar, making her act early. On turn, she grants ability energy to A.I.M. or Orchis allies with negative effects (more with T4). She has a 25% chance to revive an ally at 30% Health. On ally summon, she grants ability energy to all Orchis allies.
In Raids, she generates ability energy for herself and Orchis allies on spawn, blocks Trauma for her team, and prevents Immunity on Mutant and Bio enemies.

Basic – Serum Pistol, attacks the primary target, applying Offense Down and Defense Down. T4 ensures Offense Down, Defense Down, and Slow. It’s unavoidable and slightly boosted with T4.

Special – Field Trials, heals all allies, stronger in Raids. Flips 3 negative effects (all with T4), grants Regeneration, Immunity, and boosts buffs. Debuffs all enemies, applies Trauma in Raids (T4 required), and grants Speed Up to Orchis allies. Unavoidable with bonus Focus.

Ultimate – Retro Vaccination, heals and flips all negatives to positives for all allies. Grants Regeneration, Immunity, and extends buffs. Heals for 15% Max Health—ideal with Healer Iso-8.

Iso-8 Recommendations

For Scientist Supreme in Marvel Strike Force, the top Iso-8 class choices are Healer, Fortifier, and Skirmisher. Healer is the most recommended, as it amplifies her strong healing abilities and scales with her Max Health something she already benefits from. The class also grants additional Max Health at certain levels, further boosting her sustain and making her a reliable support option for your team.

Fortifier adds survivability by granting a Barrier based on her Max Health, making her harder to take down ideal if you’re leaning into durability. Skirmisher is a more offensive choice, helping apply Vulnerable with her debuff-heavy kit and counter-attacks, though she already has bonus Focus on her own. Your best option depends on your team needs: go Healer for support, Fortifier for tankiness, or Skirmisher for added damage potential. Regardless of the class, increasing Health and Potency will improve her healing and debuff reliability.

Team Synergies and Usage

Scientist Supreme’s effectiveness in Marvel Strike Force is largely dependent on her team composition, with a strong focus on her affiliations with A.I.M. and Orchis. Her recent rework has solidified her role as a linchpin, especially within the Orchis team, which is designed to excel in raid content.

Initially, Scientist Supreme was part of the A.I.M. faction, which had a less favorable reputation early on in the game. While A.I.M. is still considered somewhat niche, she remains a valuable asset in Alliance Wars on defense, where her abilities to heal, flip debuffs to buffs, and revive allies contribute significantly to team sustainability and disruption. However, her potential is now more prominently highlighted with the Orchis team.

Scientist Supreme plays a central role within the Orchis raid team, working seamlessly with characters like Lady Deathstrike, Sentinel, Nimrod, and Omega Sentinel. The team is specifically tailored for Orcus raids, where her abilities provide a strong advantage. Her passive ability is particularly useful, generating energy for Orchis allies with negative effects and offering a revive chance on ally summon, synergizing well with Sentinel's summoning capabilities.

Scientist Supreme is a vital support character in the Orchis raid team, offering healing, debuff control, and energy generation. Her ultimate applies Trauma in raids, preventing enemies from cleansing debuffs and allowing her team to maintain their buffs. Her special heals, flips negative effects, and grants Regeneration, Immunity, and Speed Up to Orchis allies crucial for sustaining through difficult encounters. With a T4 upgrade, she and all Orchis allies become immune to Trauma, ensuring consistent debuff flipping and greater raid stability.

Her passive ability gives her a 50% Speed Bar on spawn, letting her act quickly and activate key abilities early in battle. She also generates three special ability energy for all Orchis allies at the start of raids, enabling the team to unleash their most powerful skills right away. Additionally, she blocks Immunity on mutant and bio enemies in raids, improving the team’s ability to land debuffs effectively.

While she’s not typically used solo in Dark Dimension, she can still be a strong asset when paired with three to four Orchis allies. Her healing, speed, and ability to flip debuffs remain valuable in team-based content. Building up her Health boosts her healing output, and increasing Potency improves her debuff application. Post-rework, Scientist Supreme has become a cornerstone of the Orchis raid team, offering utility that’s hard to replace in both raids and high-end PvE content.

T4 Ability Priority

Next → Back

Recommended T4 order: Passive > Ultimate > Special > Basic.

Stats and Progression

Scientist Supreme's stats in Marvel Strike Force are essential to her effectiveness, and understanding her progression is key to maximizing her potential. Her stats evolve as she is leveled up, geared to higher tiers, equipped with Iso-8 enhancements, and gains red star promotions. Her recent rework has significantly impacted her stats, making her even more formidable in battle.

Scientist Supreme has a mix of offensive and defensive stats that contribute to her overall performance. Her offensive stats include Damage, Speed, and Focus, while her defensive stats consist of Health, Armor, and Resistance. Before her rework, her offensive stats were considered underwhelming, which is typical for support characters. Her speed was low, rated as 'D', indicating she benefited from team speed buffs. Her focus was decent, given her debuffing abilities. Defensively, she had a surprisingly large health pool for a support class, rated as 'S'. Her armor and resistance were more mid-range, with both rated 'C'. Prior to the rework, her speed stat was 97.

As Scientist Supreme levels up, all of her base stats improve, with gearing up being a significant contributor to boosting her stats, including health, damage, armor, focus, and resistance. The progression through gear tiers is crucial, especially for surviving high-difficulty content like raids. Players have reported gearing her up to gear tier 18 or 19 pre-rework, and this continues to be important post-rework.

Iso-8 Modifications further enhance her stats, with the primary focus being on Health, as her healing abilities scale with her max health. Adding 1,000 health from Iso-8 can translate to an extra 150 health healed to each ally when she uses her special ability. Potency is another area to focus on to ensure her debuffs land effectively. Armor can supplement Health to increase her survivability. Both the Healer and Fortifier Iso-8 classes provide +10% Max Health at certain levels, making them strong choices.

Red Star Promotions boost a character’s base stats, with higher red star counts offering more substantial increases.

The rework of Scientist Supreme led to massive stat increases across the board. Her Power went from 627,269 to 1,082,014, and her Health saw an astronomical increase from 1,846,920 to 10,080,989, a jump considered "insane" by many players. Her Damage increased from 99,730 to 521,589, her Armor rose from 30,509 to 312,710, her Focus improved from 21,517 to 116,185, and her Resistance went from 35,933 to 113,497. Additionally, her Speed increased from 97 to 118, making her significantly faster and allowing her to take action early in battle. These changes were likely made to compensate for the lack of significant team-wide stat bonuses in the Orchis team, where she plays a pivotal role.

Post-rework, the primary stat priorities for Scientist Supreme remain Health due to its direct impact on her healing abilities. Focus is also crucial to ensure her important debuffs, such as Offense Down, Defense Down, and Slow, land consistently. Survivability through increased Health and Armor/Resistance is vital for ensuring she can remain effective throughout extended raid encounters.

In conclusion, Scientist Supreme has undergone a dramatic transformation in her stats post-rework, particularly in her Health. Progressing her through leveling, gearing, Iso-8, and red stars will further enhance these stats, making her an even more powerful support character, especially in the Orchis raid team. Prioritizing Health and Focus through Iso-8 and gear choices will help maximize her overall effectiveness.

Overall Assessment and Tips

Scientist Supreme has transformed from a niche support to a crucial part of the Orchis raid team. Her rework boosted her stats, added a 50% Speed Bar on spawn, and improved her healing, debuff-flipping, and energy generation making her a top-tier support in raid content.

Strengths and Best Use, Her speed lets her act early, applying Trauma, flipping debuffs, and supporting the team with Immunity, Speed Up, and energy. She shines most in Orchis Raids, Ultimus 7, and Greek Raids. While still functional with A.I.M. or in Alliance War Defense, she’s less effective solo or in Blitz and Arena.

Pair her with core Orchis members like Sentinel, Nimrod, Omega Sentinel, and Lady Deathstrike for best results. Use Healer or Fortifier Iso-8 to boost her health and survivability. T4 upgrades to prioritize are her Passive, Ultimate, and Special all crucial for raid success. Focus on Health and Potency to maximize her healing and debuff accuracy. With the right setup, Scientist Supreme is a must-have support for tough raid content and a key part of any high-performing Orchis team.

Frequently Asked Questions (F.A.Q)

🧪 Who is Scientist Supreme in Marvel Strike Force?

Scientist Supreme is a powerful support character, especially effective after her rework. She excels at healing, flipping debuffs, applying key status effects, and enabling the Orchis raid team.

🛡️ What Iso-8 class is best for Scientist Supreme?

Healer is the top pick for maximizing her healing, while Fortifier offers more survivability through Barriers. Skirmisher is less effective due to her support-focused kit.

🔧 Which T4 abilities should I upgrade first?

Prioritize her Passive (prevents Trauma for Orchis allies and gives extra energy), Ultimate (applies Trauma to enemies), and Special (flips all negative effects). Her Basic is less essential.

🧬 What are her most important stats to build?

Health is critical, as it scales her healing. Focus ensures her debuffs land, and Potency boosts her overall effectiveness in control and healing roles.

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About the Author

Angelo P

Angelo P, a passionate gamer who’s all about Dota and RPGs, especially those with captivating stories. Since 10 years old, Angelo has been playing Dota and found the competitiveness of players to be very enjoyable. For RPGs, he has a strong preference for games that have a good story. Current favorites are Metaphor and Triangle Strategy. Angelo believes that gaming is more than just playing, it's about experiencing stories that stick with you long after the game is over. Login Please login to comment 0 Comments Inline Feedbacks View all comments