The Tysis is one of Warframe's older secondary weapons. First introduced in Update 11.7, this Infested pistol fires explosive darts that debuff targets with a myriad of status ailments, notably Corrosive. If you need to debuff a tough boss or melt some fodder units, the Tysis won't let you down.
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PostsWhile this weapon has more or less been forgotten about in recent years, the Tysis still packs a serious punch once you gain access to endgame mods and Forma. In this guide, we'll be going over how to turn the Tysis into a strong secondary workhorse for Steel Path and beyond, covering everything from weapon stats to endgame builds.
Updated March 29, 2025, by Charles Burgar: The Coda Tysis is now available with Warframe's latest 1999 update, giving players access to upgraded variants of some old-school Infested gear. We've updated this guide to include stats for the Coda Tysis and an endgame build that best utilizes its upgraded stats.
How To Craft The Tysis
The Tysis can be crafted by purchasing its blueprint in the in-game marketplace. Its main blueprint costs 30,000 Credits and may be purchased at any time. You'll need to be Mastery Rank 9 to use this weapon. All crafting requirements for the Tysis can be found below.
Once you unlock Hollvania, you can farm Technocyte Coda Liches to get your hands on the Coda Tysis, featuring significantly more base damage and higher critical stats. This version does not need to be crafted and comes with a progenitor bonus, granting it an additional damage type.
Tysis Crafting Requirements
2 Neurodes
400 Plastids
900 Nano Spores
100 Polymer Bundle
Credit Cost: 30,000
Build Time: 24 Hours
Tysis Stats And Features
Base Damage
Tysis
Coda Tysis
Impact
9
18
Puncture
23
32
Slash
17
26
Corrosive
27 (x3)
59 (x3)
Total
130
253
Other Damage Stats
Multishot
1
1
Fire Rate
2.5
2.5
Critical Chance
3%
13%
Critical Multiplier
1.5x
2x
Status / Projectile
50%
50%
Misc.
Weapon Type
Pistol
Trigger Type
Semi
Accuracy
Very High
Magazine
11
18
Reload Speed
1.2s
1.2s
MR Requirement
Mastery Rank 9
Mastery Rank 17
The Tysis is a semi-auto pistol that fires explosive darts which embed into targets, detonating into a Corrosive DoT after a short delay. While this weapon has pitiful base damage for a secondary, it has an absurdly high status chance of 50% base. Projectile detonations deal 27 Corrosive damage per second for three seconds and inherit the base shot's 50% status chance, leading to a copious number of status ailments with a good build.
In essence, the Tysis is a status prime. It's not a hard-hitting weapon by default, but you can greatly improve this weapon's performance with Galvanized mods once you hit the endgame, notably with Galvanized Shot. It's also a decent critical/status hybrid once you get the Coda variant.
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PostsTysis Build
There are two builds we'll be looking at in this guide. The first build is for the standard Tysis and will easily get you through Arbitrations and the majority of Steel Path content. The second build is tailored for the Coda version, featuring a handful of critical mods to further scale this weapon's DPS.
Status Primer Build
Forma
None
Variant
Tysis
While this build doesn't use any Forma, the Tysis is surprisingly powerful once you get access to Galvanized mods. Until then, standard mod variants will work just fine, although you'll struggle to clear Steel Path content.
Galvanized Shot is hands-down the strongest mod on this build, scaling your base damage off the status ailments on the target. We then use three elemental mods—your choice, but make sure they're element/status hybrid mods like Frostbite and Scorch—to give this weapon a wide range of damage types. Throw on some multishot with Galvanized Diffusion and Lethal Torrent, and now the Tysis can inflict dozens of status ailments in seconds.
As for elemental types, we recommend Viral + Heat for most content. Corrosive already shreds enemy armor, so scaling HP damage through Viral makes for a deadly combination. Blast is also fantastic here since you inflict so many status ailments. Pick whichever elements best exploit your enemy faction's vulnerabilities.
Coda Endgame Build
Via: OverframeForma
5 (4V, –)
Variant
Coda Tysis
This build uses a few critical mods to give the Coda Tysis a 37 percent critical chance with a 4.2x multiplier. That chance is somewhat low for a secondary, so we also recommend you run Arcane Avenger on your Warframe to get an extra 45 percent critical chance, bringing your total to 82 percent.
The rest of the build is mostly the same as before. Galvanized Aptitude greatly buffs your damage per hit, especially when paired with Secondary Merciless. We then use Galvanized Diffusion for multishot, Lethal Torrent for fire rate, and Primed Heated Charge with Frostbite for added Blast damage. You can run Primed Convulsion in the last slot for added electric damage, but feel free to use any mod in its place.
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