Shin Megami Tensei 5: Vengeance shakes things up on abscesses relative to the original 2021 version of the game. Abscesses no longer keep portions of the game's sprawling regional maps enshrouded in mystery until they're destroyed, so they're a good bit more optional now than they were before.

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But should you ignore them? Absolutely not! Every time you seal one off, your stock of available Miracles widens over in the World of Shadows. Miracles come in many forms, plenty of which are game-changers. Since Shinjuku is brand-new to Shin Megami Tensei 5: Vengeance, we've assembled this guide to help you find its abscesses.

All Shinjuku Abscess Locations

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All Shinjuku Abscess Locations

Gyoen

You'll find Gyoen's abscess not far from the Aogami husk nearest to Shinjuku's entry point. Notably, a group of Succubi rotates around a pillar to the southeast of this location.

Yoyogi

The Yoyogi abscess is in the very northeasternmost corner of the map, at the end of a path that will require a fair bit of climbing.

Kabukicho

Kabukicho is the northern central area in Shinjuku, and it's technically even further north than Yoyogi's abscess. Along the middle of the western border of the area, you'll find this abscess.

Sendagaya

In the southeast corner of the map, where "The Horn of Plenty" side quest's Chimera fight is located. This is also almost due south from where you initially enter Shinjuku.

Yotsuya

From Gyoen (the first leyline you unlock), keep close to the wall as best you can while heading northeast. It's at a jutting-out area roughly a third of the way to the Yoyogi abscess.

3rd Block

If this is your first time in the Shinjuku 3rd Block area, you'll need to weave around a few city blocks northwest of the leyline before you can reach this, since the path is kind of tangled, and you can't get to it by veering southbound.

If you've already unlocked multiple railways, you can simply take the railway near the 3rd Block leyline, then take one more that follows up on it, and you're almost there.

Near Government Building

Depending on where you are in the story, this last abscess can be either deceptively difficult to reach than the Government Building close to its east, or easier than getting to the Government Building itself.

This is because the abscess is about midway up the farthest-west zone, near the western boundary line. We were able to get here before we even figured out how to get to the Government Building.

You'll likely need to have found numerous railways, the nearest duo of which are to the south of the abscess and visible in our screenshot.

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