Have you accidentally been hit with a damaging Ailment, or have you buffed yourself but you don’t know how it worked? We’ll explain all positive and negative Ailments in Last Epoch and what they do.

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Ailments will affect both you and your enemies in various ways, depending on which type it is. They can either be good or bad for the target too. Here’s how they all work.

All Ailments in Last Epoch, explained

Ailments in Last Epoch are debuffs and buffs that will either negatively or positively affect you or your enemies. Negative Ailments will either weaken or damage the target, but positive Ailments will buff the target. Because there is such a variety of Ailments in this game, it’s hard to narrow them all down. Otherwise, here are all the main positive and negative Ailments in Last Epoch.

All negative Ailments

AilmentAffectBase damageDurationMax stacksAbyssal DecayDeals Void damage over time.120Six secondsOneAcid SkinDeals Poison Damage over time and +20% chance to receive Critical Strike.80Five secondsOneAnguishDeals Necrotic Damage over time and causes target to deal 15% less damage over time.4010 secondsOneBleedDeals Physical Damage over time.53Three secondsNo limitBlindReduces Critical Strike chance by 50% and makes ranged enemies unable to aim correctly.–Four secondsOneChainedImmobilizes target and deals Necrotic Damage over time.40Two secondsOneChillReduces attack, movement, and cast speed by 12% per stack.–Four secondsThreeCritical Vulnerability+2% chance to receive Critical Strike and reduces Critical Strike Avoidance by 10%.–Four seconds10DamnedDeals Necrotic Damage over time and reduces Health regen by 20%.352.5 secondsNo limitDoomDeals Void Damage over time and increases Melee Damage taken by 4%. 400Four secondsFourElectrifyDeals Lightning Damage over time.442.5 secondsNo limitFearForces the target to run away in fear.–Five secondsNo limitFrailtyDeal 6% less damage.–Four secondsThreeFreezeUnable to move or make actions.–1.2 secondsOneFrostbiteDeals Cold Damage over time and increases the chance of being Frozen by 20%. Only the first 30 stacks increase Frozen chance.36Three secondsNo limitIgniteDeals Fire Damage over time.402.5 secondsNo limitLacerationDeals Melee Damage over time.OneThree secondsOneMarked For DeathReduces all Resistances by 25%.–Eight secondsOnePenanceMakes target take Fire Damage over time when they hit a target.2015 secondsOnePlagueDeals Poison Damage over time and spreads between enemies.150Four secondsOnePoisonDeals Poison Damage over time and reduces Poison Resistance by 5%. Only the first 30 stacks reduce Poison Resistance.20Three secondsNo limitShred ArmorReduces Armor by 100.–Four secondsNo limitShred [X] ResistanceReduces specific Resistance by 5%.–Four seconds10SlowReduces movement by 20%.–Four secondsThreeSpirit PlagueDeals Necrotic Damage over time and spreads to another enemy upon death if not expired.90Three secondsOneTime RotDeals Void Damage over time and increases the duration of Stuns received by 5%.55Three seconds12TormentDeals Necrotic Damage over time and reduces Movement Speed by 18%.12Three seconds1WitheringCauses the target to take +10% Curse Damage.–Three seconds20

Related: Last Epoch: Item Rarities, explained

All positive Ailments

AilmentAffectDurationMax stacksAncient Flight+2 arrows to Flurry and Multishot when using a bow, 100% increased Critical Strike Chance, and 100% increased Critical Strike Avoidance.Two secondsOneApocalypse+70% Void Damage and Melee Critical Strike Multiplier.Three secondsOneAspect of the Crow+3 Melee and Spell Lighting Damage.Eight secondsNo limitAspect of the Spider+100% chance to Slow on hit, and 15% more damage to Slowed enemies.Eight secondsOneContempt+10% to Resistances and Armor.500 secondsFiveCrimson Shroud+50% chance to Bleed on hit and 5% less damage over time taken.Four secondsThreeCritical Effluence+100% Spell Critical Strike ChanceSix secondsOneCritical Shrine+100% Critical Strike Chance.60 secondsOneDivine Essence+10% Armor and Healing Effectiveness, and 10% reduced duration of Stuns received10 secondsThreeDusk Shroud5% chance to receive a Glancing Bow when hit, and +50 Dodge Rating.Four secondsNo limitEnrage+60% Attack and Cast Speed, and +35% Movement Speed.Six secondsOneFerocity+50% Physical Damage.Four secondsOneFrenzy+20% Attack and Cast Speed.One secondOneHaste+30% Movement Speed.Four secondsOneInspiration+20% Cooldown Recovery Speed.Four secondsOneLighting Infusion+21 Lighting Damage.Four secondsThreeMolten Infusion+15 Melee Fire Damage and +30% chance to Ignite on hit.Four secondsNo limitSciurine Rage+40% Movement and Melee Attack Speed.Four secondsOneShapeshifter+50% Damage and Armor.Four secondsOneSharpshooter+25% Bow Damage.Eight seconds10Silver ShroudDodge your next hit and gain Ward per stack.10 secondsNo limitSmoke Blades+4 Melee and Throwing Damage.Four secondsNo limitSpirit Kindling2% current Health Drained per second, but +20% Movement Speed and +10% Melee Attack Speed.Five seconds100Talon Blades+6% Critical Strike Chance and +3% Critical Strike Multiplier18 secondsNo limitVoid Essence+15% Void and Melee damage, and 10% reduced duration of Stuns received.Seven secondsThreeWater Shrine+100% Mana Regen and Cooldown Recovery Speed.45 secondsOne

Another thing you may be confused about is the Ward stat in Last Epoch, which we have a guide on to explain what this is.

Last Epoch